The event was spread out across the entirety of the large city centre venue with the traders' hall being held in the large Cromdale Hall area, the celebrity guest area and prop builds in the larger Lennox Suite, celebrity panel talks in the Sidlaw Auditorium and the cosplay competition and masquerade held in the Lammermuir Suite.

[1] However, due to the first year attendance being so high and plans for future events which would exceed the capacity of the EICC, the decision was made by Monopoly Events to move Comic Con Scotland to the much larger Royal Highland Centre, an exhibition centre and showground located at Ingliston in the western outskirts of Edinburgh, adjacent to Edinburgh Airport and the A8, allowing for a wider demographic of visitors from around the globe, higher numbers of attendance and ergo, a much higher calibre of celebrity guest, larger prop builds, additional set builds, and a larger trader area.

In 2018 during the very first Comic Con Scotland hosted by Monopoly Events in November 2018, Incredible Hulk actor Lou Ferrigno celebrated his 67th birthday alongside fellow actors Sam J. Jones, Gil Gerard, Zach Galligan, Sylvester McCoy, Herbert Jefferson Jr., and Ray Parker Jr. where the stars presented Ferrigno with a Hulk themed birthday cake.

Guests confirmed for the event to date included Alicia Silverstone, Michael Madsen, Steve Guttenberg, Joey Cramer, Frank Welker, and Peter Cullen.

Sometimes the celebrities involved will use their appearances to raise awareness and funds for a charity or cause important to them, while others use the opportunity to promote upcoming projects such as new films or television shows.

[6] Most, if not all, of the celebrity guests at Comic Con Scotland, appear on stage at some point throughout the course of the event, answering both host and fan questions alike.

At the first Comic Con Scotland event held at the Edinburgh International Conference Centre, the panels took place in a side auditorium with tiered seating.

As of the 2019 event, which was the first to take place in the new and much larger Royal Highland Centre venue, the stage is built in the main hall where anyone on the floor is free to attend the talks.

The event also includes an autograph area where celebrity guests from film and TV sign items for the public and spend a few minutes chatting with their fans.