ComicsAlliance was established in 2007 as part of an online network of sites owned by AOL, and run by editors-in-chief John Anderson and Chris Dooley.

[4] The site featured writing from critics including David Brothers, Andy Khouri, Caleb Goellner and Chris Sims.

In 2012 Hudson left the site, with former Vertigo Comics editor Joe Hughes later announced as the new editor-in-chief.

[8] In April 2017, ComicsAlliance was placed on hiatus by Townsquare Media and the most recent editorial staff was dissolved.

[11] Additional features of note for the site have included Kate or Die, a regular comic from cartoonist Kate Leth; as well as Best Art Ever (This Week), a weekly feature showcasing new comics-related art.