It is a shrub or tree with egg-shaped leaves that are slightly serrated on the edges, flowers with five cream-coloured to white sepals and bristly fruit.

The base of the leaf is often heart-shaped, the edges of the leaves are slightly serrated, and the lower surface is covered with velvety hairs.

Flowering occurs from August to December and the fruit is a spherical capsule 20–30 mm (0.79–1.18 in) in diameter and densely bristly.

[2][3][4] Commersonia macrostipulata was first formally described in 2006 by Gordon P. Guymer in the journal Austrobaileya from specimens collected from the Rex Range in Mowbray National Park in 2005.

[2][4] Commersonia macrostipulata grows in, or on the edges of rainforest, at altitudes of up to 800 m (2,600 ft) from Isabella Falls near Cooktown, to near Tully.