[4] Because of redundancies in the immune system, many complement disorders are never diagnosed.
[7] The following symptoms (signs) are consistent with complement deficiency in general:[1][3][10] Vaccinations for encapsulated organisms (e.g., Neisseria meningitidis and Streptococcus pneumoniae) is crucial for preventing infections in complement deficiencies.
[medical citation needed] Among the possible complications are the following: The cause of complement deficiency is genetics (though cases of an acquired nature do exist post infection).
The majority of complement deficiencies are inherited as autosomal recessive conditions, while properdin deficiency occurs through X-linked inheritance.
[2] Epsilon-aminocaproic acid could be used to treat hereditary C1-INH deficiency, though the possible side effect of intravascular thrombosis should be weighed.