HTCondor runs on Linux, Unix, Mac OS X, FreeBSD, and Microsoft Windows operating systems.

HTCondor can integrate both dedicated resources (rack-mounted clusters) and non-dedicated desktop machines (cycle scavenging) into one computing environment.

Starting from version 7.1.1, HTCondor can hibernate and wake machines based on user-specified policies, a feature previously available only via third-party software.

[3] HTCondor was the scheduler software used to distribute jobs for the first draft assembly of the Human Genome.

The NASA Advanced Supercomputing facility (NAS) HTCondor pool consists of approximately 350 SGI and Sun workstations purchased and used for software development, visualization, email, document preparation, and other tasks.