The General Confederation of Italian Industry (Italian: Confederazione Generale dell'Industria Italiana), commonly known as Confindustria, is the Italian small, medium, and big enterprises federation, acting as a private and autonomous chamber of commerce, founded in 1910.

It aims to help Italy's economic growth, assisting, in doing so, its members.

Confindustria was a founding member of several organizations, including ISTUD (Istituto Studi Direzionali) and Assingegneria (an organization set up by Confindustria, which has since merged with OICE, L'ingegneria italiana organizzata - which in itself belongs to Confindustria).

Members of Confindustria include ANIMA, the Federation of the Italian Associations of Mechanical and Engineering Industries.

It owns the prominent newspaper Il Sole 24 Ore. With local chapters all over Italy, it is popularly synonymous with Italian business.