[2] It has also been categorized as a soft-rot fungus capable of bringing the surface layer of timber into a state of decay, even when safeguarded with preservatives.

[6] The genus Lecythophora, originally described by John Axel Nannfeldt in 1934, was reintroduced by Konrad Walter Gams and Michael R. McGinnis to accommodate this species in 1983.

This allows for the utilization of part of the amorphous granular material, found in said phenolic compounds, which contains the lignin breakdown products produced in soft-rot activities.

[9] Alternatively, flask-shaped lateral cells, which are practically cylindrical, can serve as the medium through which conidia are produced; they are sometimes found to be arranged in densely packed groups.

[9] Coniochaeta hoffmannii rarely causes disease, but when it does, it is only seen in immunocompromised patients, thus marking it as an opportunistic fungal pathogen.

While great advances in medical technology have decreased previously high rates of morbidity and mortality, the amount and variation of opportunistic pathogens has also increased.

The patient in question was immunocompromised and thus severely immunodeficient due to contracting the human immunodeficiency virus; this allowed for the fungal pathogen to not only infect the patient (where an intact immune system would have made an infection by C. hoffmannii a non-issue), but inflict a recurrent, chronic disease such as sinusitis.

In humans, C. hoffmannii is not only the causative agent when it comes to original infection, but it also exacerbates the symptoms upon administration of antifungal treatments.

[17] Coniochaeta hoffmannii has proven to be resistant to multiple antifungal agents, including amphotericin B, flucytosine, ketoconazole, and fluconazole.

Through this method, polyhexamethylene biguanide (PHMB) has been identified and utilized in conjunction with invasive surgical procedures to successfully treat one of the only cases of infection at the hands of this fungus.