The site includes period buildings and an orientation exhibit on a 26-acre (110,000 m2) landscaped park designed by Frederick Law Olmsted Jr.
A family cemetery behind the house is the final resting place of Weiser, his wife Anna and many friendly Indian Chiefs.
Soon after Conrad's birth, his father received a discharge from the Blue Dragoons and moved back to the family ancestral home of Gross Aspach.
Fever claimed the life of his mother, Anna Magdalena, in 1709 after war, pestilence, and an unusually cold and long winter ravaged the lands.
Wallace notes that Conrad Weiser (senior) wrote for his children, "Buried beside Her Ancestors, she was a god-fearing woman and much loved by Her neighbors.
During his stay with them in the winter and spring of 1712–1713, Weiser endured hardships of cold, hunger and homesickness, but he learned a great deal about the Mohawk language and the customs of the Iroquois.
In 1723 the couple followed the Susquehanna River south and settled their young family on a farm in Tulpehocken near present-day Reading, Pennsylvania.
During the treaty in Philadelphia of 1736, Shikellamy, Weiser and the Pennsylvanians negotiated a deed whereby the Iroquois sold the land drained by the Delaware River and south of the Blue Mountains.
Since the Iroquois had never until then laid claim to this land, this purchase represented a significant swing in Pennsylvanian policy toward the Native Americans.
During this council, the Onondaga chief Canasatego castigated the Lenape for engaging in land sales, and ordered them to remove their settlements to either the Wyoming Valley or Shamokin village.
In 1744, Weiser acted as the interpreter for the Treaty of Lancaster, between representatives of the Iroquois and the colonies of Pennsylvania, Maryland and Virginia.
During the final day of the treaty, on 1744-07-04, Canasatego, the Onondaga chief, spoke of the Iroquois concepts of political unity: "Our wise forefathers established Union and Amity between the Five Nations.
Early in the summer of 1754, on the eve of the French and Indian War, Weiser was a member of a Pennsylvania delegation to Albany.
Weiser was able to negotiate one of the more successful, in which some lower-level chiefs deeded to the colony most of the land remaining in present-day Pennsylvania, including the southwestern part, still claimed by Virginia.
This collapse of Native American support was a factor in the French decision to demolish Fort Duquesne and withdraw from the Forks of the Ohio.
Because of his early experiences with the Iroquois, Weiser was inclined to be sympathetic to their interpretation of events, as opposed to the Lenape or the Shawnee.
The Conrad Weiser Homestead includes period buildings, and a new orientation exhibit, on a 26-acre (110,000 m2) Olmsted-designed landscaped park.
Weiser was predominantly responsible for negotiating every major treaty between the colonial settlers in Pennsylvania and the Iroquois Nations from 1731 until 1758.
In addition to serving as one of the most knowledgeable and successful liaisons between the Indian and the colonist, Weiser was chiefly responsible for both the settlement of the town of Reading, Pennsylvania and the establishment of Berks County.
Exempting some Berks County locals and various individuals with genealogical ties to this man, few are conscious about the relevance, let alone the existence, of Conrad Weiser.
Conrad attained significant knowledge of not only the language but also the customs and traditions of the Mohawk tribe, which proved invaluable later in his career.
Weiser moved to the Tulpehocken area in Pennsylvania in 1729, erecting a house upon a farmstead that would eventually contain 890 acres (3.6 km2) of land.
Weiser’s success in mediating Indian/Colonial politics established a tremendous ethos of credibility in the eyes of the Pennsylvania Government.
An incident in 1755 known as the “Penn’s Creek Massacre” left several colonials dead and many others missing in the wake of Indian attacks in northern Pennsylvania.
Weiser conducted his final substantial contribution to Indian/Colonial diplomacy in 1758, negotiating the Treaty of Easton, which concluded the vast majority of Indian insurrection in the eastern third of Pennsylvania.
Weiser’s body currently resides in a family burial plot to the west of what was believed to have been his house in the Tulpehocken area.
He created the plan for the city of Reading in 1748, was a key figure in the creation of Berks County in 1752 and served as its Justice of the Peace until 1760.