Constantin Frățilă was born on 1 October 1942 in Bucharest, Romania and he started to play football in 1957 at local club, Recolta, after one year moving to Uzinele Vasile Roaită.

[2] He started his senior career playing for Dinamo București, making his Divizia A debut on 16 April 1961 in a 6–0 victory against Minerul Lupeni in which he scored a hat-trick, having a total of seven goals in seven appearances until the end of his first season spent at the club.

[2][3][4][5][6][7][8][9][13] During his 10 seasons spent at Dinamo, Frățilă scored in the league six goals in the derby with Steaua, including a brace in a 3–2 victory but in a 1967 Bucharest Cup match against them he suffered an injury which kept him off the field for one year and a half.

[3][8][14] In 1970 he went to play for Argeș Pitești where in his second season he helped the team win the Divizia A title, contributing with seven goals scored in the 17 matches coaches Titus Ozon and Florin Halagian used him.

[16] Frățilă made his last appearance for the national team on 22 March 1967 in a friendly which ended with a 2–1 victory against France in which he scored a goal.