Between 1885 and 1887 the Plaza Constitución terminus was rebuilt and enlarged and between 1906 and 1907 further building work was carried out and extra platforms were added to cope with the increasing suburban traffic.

On 19 September 1925 a foundation stone for the present day terminus was laid by the Prince of Wales, later Duke of Windsor, during his official visit to Argentina.

The original station was then rebuilt with fourteen platforms roofed over, modern hydraulic buffer stops and an imposing concourse which formed a massive main hall, one of the largest in the world, along the entire length of the site.

The street frontage of the original station was left untouched due to financial constraints imposed towards the end of the rebuilding.

The station was the site of a riot on May 16, 2007, during the evening rush hour, which provoked debate and discussion in Argentina about railway privatisation.

Major destinations include Mar del Plata, Miramar, and Bahía Blanca, with connecting services further south to Carmen de Patagones.