The Copano were a Native American sub-tribe of Karankawa peoples from Texas.

[1] The Copano were also known as the Cobane, Copane, Coopane, and Kopano Indians.

[1] El Copano Port was named for the tribe, who lived in the area in the 18th century.

[2] Between 1751 and 1828, the Kopano interacted with the Nuestra Señora del Rosario and Nuestra Señora del Refugio Missions.

[1] Those that survived the mission era likely merged into other Karankawa groups, but by 1858 all Karankawa tribes had died off.