The basic plot go as follows: An adventurous girl named Coraline Jones has moved to the Pink Palace Apartments with her parents, Charlie and Mel, where she, longing for adventure eventually finds a mysterious parallel universe where all of her dreams and desires are fulfilled by a malevolent creature known as "the Beldam" or the "Other Mother".

The game's score was composed and produced by Mark Watters, and was recorded and mixed by Tim Bryson at Robert Irving Studios (based in Woodland Hills, Los Angeles) and Watter Music (based in Chatsworth, Los Angeles).

The only three actors to reprise their roles from the film are Dakota Fanning as Coraline, Keith David as the Cat and Robert Bailey Jr. as Wyborn "Wybie" Lovat.

The remaining roles are occupied by voice actors Kath Soucie, Amanda Troop, JB Blanc, Susanne Blakeslee and Dave Foquette.

Unlike the critically acclaimed film, the DS version received "mixed" reviews, earning a score of 50/100.