The song was written, produced and sung by Fher Olvera, and co-produced by Alex González, and was released on May 30, 2000, as the fifth single from their 17th studio album, Supernatural (1999), and became a top-20 hit in Italy and Spain.

It won the "Record of the Year" and "Best Rock Performance by a Duo or Group" at the 2000 Latin Grammy Awards.

In February 2007, her official website launched a poll for fans to decide which song they wanted to have as the next radio single from Mayre's debut album, Soy Mi Destino, the winner song was the studio-recorded cover of "Corazón Espinado".

In the last few days of July 2007, the song gained heavy radio-airplay in all Latin America.

Mayré performed the track in the third workshop episode of the second season of Latin American Idol, where she also presented her first album.