The Penibaetic System (Spanish: Sistema Penibético or Cordillera Penibética[1]) is the southernmost of the three systems of mountain ranges of the Baetic System in the southern Iberian Peninsula.

It includes the highest point in the peninsula, 3,478 m high Mulhacén in the Sierra Nevada.

[2] The Penibaetic System runs along the south coast of Andalusia, from the province of Cádiz, across the province of Granada, into the Region of Murcia until reaching the Campo de Cartagena.

Along its northern side, across the intermontane basins known as the Hoya de Baza and the Hoya de Guadix, runs the Subbaetic System.

The Intrabaetic Basin (Spanish: Surco Intrabético), a discontinuous series of valleys, separates the Cordillera Penibética from the Cordillera Subbética in the north.