It is found primarily in the east-central United States, from Maryland south to Georgia, with isolated populations as far west as Oklahoma and as far north as Québec and Ontario.

[7] Coreopsis verticillata can commonly be found in dry, thin woods and open pinelands, preferring sites with full sun exposure.

[6] Coreopsis verticillata and its horticultural cultivars are not difficult to grow and hence make good starter plants for beginning gardeners in the U.S.[8] They have a long flowering season and are relatively free from pests and diseases.

[9] Carolyn Singer, in "Deer in My Garden", reports that C. verticillata is a good companion plant with other summer-blooming perennials requiring similar conditions.

[10] The following notable cultivars have gained the Royal Horticultural Society's Award of Garden Merit: