Its academic partner is University College Cork and serves as one of two major trauma centers for Ireland.

Work began on constructing the hospital, located in the south of the CUH site by the main entrance, in 2001.

[5] This facility brought together maternity services previously located at the Bon Secours, Erinville and St. Finbarr's Hospitals.

[7] The hospital's Cardiac Renal Centre, built at a cost of €85 million, opened in October 2010.

[18] A number of Bus Éireann city bus routes serve the hospital, including routes 201 and 208 (from Mayfield), 214 (from St Patrick's Street), 216 (from Monkstown via Douglas), and 219 (from Mahon).