He was born in Wouw, the second son of John II of Glymes (1417–1494), Lord of Bergen op Zoom, and his wife Margaretha of Rouveroy.
He also commanded the fortress of Grave, an important Habsburg stronghold in the war against Guelders.
Between 1490 and 1491, he was Admiral of the Netherlands, and participated in the submission of the Flemish rebellion against Maximilian of Austria.
In 1501, Philip the Fair made him a Knight in the Order of the Golden Fleece.
They had the following issue: He also had an illegitimate and post mortal daughter : Geertrui of Bergen (1510–1541)