[2] Agrippa's academic career began in 1509, receiving the patronage of Margaret of Austria, governor of Franche-Comté, and Antoine de Vergy, archbishop of Besançon and chancellor of the University of Dole.

[4] At Dôle, Agrippa wrote De nobilitate et praecellentia foeminae sexus (On the Nobility and Excellence of the Feminine Sex), a work that aimed at proving the superiority of women using cabalistic ideas.

In 1510 the king sent Agrippa on a diplomatic mission to England, where he was the guest of the Humanist and Platonist John Colet, dean of St Paul's Cathedral, and where he replied to the accusations brought against him by Catilinet (Expostulatio super Expositione sua in librum De verbo mirifico).

Here, as at Dôle, his opinions soon brought him into collision with the monks, and his defense of a woman accused of witchcraft involved him in a dispute with the inquisitor, Nicholas Savin.

In 1528 he gave up this position, and about this time was invited to take part in the dispute over the legality of the divorce of Catherine of Aragon by Henry VIII; but he preferred an offer made by Margaret, duchess of Savoy and regent of the Netherlands, and became archivist and historiographer to the emperor Charles V.[3] Margaret's death in 1530 weakened his position, and the publication of some of his writings about the same time aroused anew the hatred of his enemies; but after suffering a short imprisonment for debt at Brussels he lived at Cologne and Bonn, under the protection of Hermann of Wied, archbishop of Cologne.

[5] It is impossible, of course, to cite negatively, but Nauert, the best bio-bibliographical study to date, shows no indication of such persecution, and Van der Poel's careful examination of the various attacks suggest that they were founded on quite other theological grounds.

For whosoever do not in the truth, nor in the power of God, but in the deceits of devils, according to the operation of wicked spirits presume to divine and prophesy, and practising through magical vanities, exorcisms, incantations and other demoniacal works and deceits of idolatry, boasting of delusions, and phantasms, presently ceasing, brag that they can do miracles, I say all these shall with Jannes, and Jambres, and Simon Magus, be destinated to the torments of eternal fire.

[citation needed] Declamatio de nobilitate et praecellentia foeminei sexus (Declamation on the Nobility and Preeminence of the Female Sex, 1529[8]), a book pronouncing the theological and moral superiority of women.

This summa of occult and magical thought, Agrippa's most important work in a number of respects, sought a solution to the skepticism proposed in De vanitate.

By this means Agrippa proposed a magic that could resolve all epistemological problems raised by skepticism in a total validation of Christian faith.

[citation needed] One example of the text, not especially indicative of its broader contents, is Agrippa's analysis of herbal treatments for malaria in numeric terms: Rabanus also, a famous Doctor, composed an excellent book of the vertues of numbers: But now how great vertues numbers have in nature, is manifest in the hearb which is called Cinquefoil, i.e. five leaved Grass; for this resists poysons by vertue of the number of five; also drives away divells, conduceth to expiation; and one leafe of it taken twice in a day in wine, cures the Feaver of one day: three the tertian Feaver: foure the quartane.

The book (whose early draft, quite different from the final form, circulated in manuscript long before it was published) is often cited in discussions of Albrecht Dürer's famous engraving Melencolia I (1514).