Boza-Edwards started boxing at the age of nine in Uganda alongside other notable fighters such as Ayub Kalule and John Mugabi.

He boxed for England but was overlooked for selection for the Olympic team after being beaten on points by Pat Cowdell in the 1976 ABA championships.

In 1981, Boza-Edwards won the WBC World Super-Featherweight Title from Rafael "Bazooka" Limón with a fifteen-round decision at Stockton, California.

[4] He defeated Bobby Chacon after he retired at the end of the thirteenth round in his first and only successful defence.

In 1982, Boza-Edwards won the European Super-featherweight title by defeating Carlos Hernandez of Spain after he retired in the fourth round.

Following his loss to Chacon he fought Rocky Lockridge the former WBA super-featherweight champion and lost on points over ten rounds.

Boza-Edwards first wife Jackie died from kidney failure six months after giving birth to their daughter Michelle in the UK.