[citation needed] The coronary sinus is responsible for venous return of about 55% of the cardiac blood supply.

[7] Dilated coronary sinus is also seen in some congenital cardiovascular conditions, such as persistent left superior vena cava,[8] and total anomalous pulmonary venous return.

[9] In Cardiac Resynchronization Therapy (CRT) procedures, a critical step involves the insertion of a pacing lead into the coronary vein system.

However, the anatomical configuration of the coronary sinus (CS) exhibits significant variability, necessitating that cardiologists assess and evaluate its characteristics during the procedure.

Complications may arise when tactical decisions must be made before the endovascular implantation of the left ventricular electrode, which can be challenging due to the unique anatomical features of the CS.