The Coronavirus 3′ UTR pseudoknot is an RNA structure found in the coronavirus genome.

Coronaviruses contain 30 kb single-stranded positive-sense RNA genomes.

The 3′ UTR region of these coronavirus genomes contains a conserved ~55 nucleotide pseudoknot structure which is necessary for viral genome replication.

[1] The mechanism of cis-regulation is unclear, but this element is postulated to function in the plus-strand.

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