On October 19, 2004, the Jetstream 32 aircraft operating the flight crashed on approach to Kirksville Regional Airport as a result of pilot error, killing 13 of the 15 people aboard.

The National Transportation Safety Board (NTSB) determined that the probable cause of the accident was: [T]he pilots' failure to follow established procedures and properly conduct a non-precision instrument approach at night in instrument meteorological conditions, including their descent below the minimum descent altitude before required visual cues were available (which continued un-moderated until the airplane struck the trees) and their failure to adhere to the established division of duties between the flying and non-flying (monitoring) pilot.The NTSB analysis of the cockpit voice recorder suggested that both pilots were looking outside the cockpit for visual cues to the location of the airport and failed to realize how low they had descended below the minimum descent altitude.

The pilots' failure to establish and maintain a professional demeanor during the flight and their fatigue likely contributed to their degraded performance.

[1]The television series Aircrash Confidential featured the incident in the third episode of Season 2, titled Pilot Fatigue.

[10] This article incorporates public domain material from websites or documents of the National Transportation Safety Board.