By month's end, the SPSL finalized a slate of six teams to start the season; the original survivors of the NPSL South Central division, plus Club América Soccer Academy Houston, Texas Lonestrikers from Nacogdoches, Texas, and a new Tulsa-based team, Tulsa Lobos FC.

Before the season ended, Texas Lonestrikers folded and Galveston Pirate SC, having reached a new agreement with the NPSL, withdrew from play.

Regals FC won the inaugural season, with five of the six top goal scorers in the SPSL playing for that club.

Two additional teams were added in time for the season: the Rio Grande Valley Ocelots FC (continuing on from their summer 2010 season in the USL Premier Development League) and the Houston Hurricane (revival of a name last used in 1980 by a team playing in the North American Soccer League).

The Ocelots won the short 2011 Spring season, with a 9–1 record and a championship game victory over Regals FC.