He made his major league debut on June 16, 2007, (although the official Orioles website states that his contract was not purchased until the next day)[1] Archived 2016-03-03 at the Wayback Machine.

Doyne's major league debut was June 16, 2007, against the Arizona Diamondbacks at Oriole Park at Camden Yards.

His first career strike out came in his second Major League game (also at Camden Yards) on July 25, 2007, against the Tampa Bay Devil Rays.

Carl Crawford, the first batter Doyne faced in the game, swung and missed on the fourth pitch of the at-bat.

Harris moved over to third base on a single by catcher Raul Casanova, and scored on a sacrifice fly off the bat of Akinori Iwamura.