Corymbia henryi is a tree that typically grows to a height of 25–30 m (82–98 ft) and forms a lignotuber.

[3] Large-leaved spotted gum was first formally described in 1977 by Stanley Thatcher Blake in the journal Austrobaileya and given the name Eucalyptus henryi.

[7][8] In 1995, Ken Hill and Lawrie Johnson changed the name to Corymbia henryi.

[9][5] The specific epithet (henryi) honours "Mr. N. Henry of the Queensland Department of Forestry".

[8][10] Corymbia henryi grows in forest, usually on more or less level country from near Brisbane and Toowoomba in Queensland to near Glenreagh in New South Wales.