Coryphodontidae is an extinct family of pantodont mammals known from the Late Paleocene to the Middle Eocene of Eurasia and North America.

[2] The type genus Coryphodon is known from around the Paleocene-Eocene transition in Europe, western United States, northern Canada, and eastern Asia.

Coryphodon are large, derived pantodonts first described in the mid-19th century, but no intermediate stages leading to their unusual upper molars are known.

[7] Corypohodontids were slow-growing and long-living animals, and studies of a large sample of individuals from a single locality, assumed to be from the same population, suggest that coryphodontids had a polygynous social structure in which males and females reached sexual maturity at different ages.

[2][8] Histological study of molar enamel samples of Heterocoryphodon flerowi and Eudinoceras mongoliensis show that their life histories were comparable to those of Hippopotamus amphibius and Ceratotherium simum, respectively.