Season two regular cast members include Courteney Cox, Christa Miller, Busy Philipps, Brian Van Holt, Dan Byrd, Ian Gomez, and Josh Hopkins.

As of July 30, 2010, former Friends star Jennifer Aniston was in talks with series producers that resulted in her reuniting on-screen with Courteney Cox.

[3] On August 9, 2010, it was confirmed that Ryan Devlin will be back for multiple episodes as Smith, newbie lawyer and love interest of Laurie.

[5] On August 10, 2010, it was revealed that Jeremy Sisto might be playing Ellie's ex-boyfriend, as Christa Miller teased that idea to her husband, the show's creator.

[6] On August 11, 2010, it was reported that Bill Lawrence is game on for a Scrubs reunion, where he said that "either Sarah Chalke, Zach Braff, John C. McGinley, Donald Faison or Judy Reyes will be on the show this year".

If that reunion episode happen, than it would mark the second time that Christa Miller and John C. McGinley worked together, as they had previously portrayed husband and wife in that show.

[7] On September 3, 2010, it was revealed that Ken Jenkins, who previously worked with the show's creator Bill Lawrence in Scrubs, will be portraying Jules father on the Halloween-themed episode, scheduled to air on October 27, 2010.

[10] On November 2, 2010, it was reported by Matt Webb Mitovich, from Fancast, that newcomer Jennifer Cortese is playing Grayson's ex-wife Vivian, and her first appearance will be on the Thanksgiving episode, When the Time Comes.

On May 11, 2010, the show's creator, Bill Lawrence, said that he was considering changing the series' title since the name Cougar Town wasn't well received by the viewers.

[16] Tim Stack from Entertainment Weekly regarded the season in a positive light, citing that "very few shows can get away with genuine moments of emotion while also incorporating the phrase 'dead-baby tacos.'"

Jules pays a lot of attention to Grayson; Travis asks Bobby for advice about how to behave at college; Ellie's new nanny suddenly becomes too friendly with her, and Laurie might have something to do with this.

Bobby says that he would be beyond happy in helping them, but Ellie had revoked his title as Stan’s emergency legal guardian after he and Jules got divorced.

Jules decides to host a romantic dinner at Thanksgiving to make Grayson say "I Love You" to her; Ellie and Laurie spoil Andy's optimism; the gang reveals that it's hard to understand what Bobby says most of the time, bringing him down.

Jules tries to help Bobby regain his confidence; Ellie finds a hilarious secret of Grayson's; Kirsten is jealous of Travis and Laurie's relationship.

Jules begins to question her relationship with Grayson; Kirsten throws Bobby off his golf game; Ellie is upset that Andy used their personal joke on Laurie.

On Valentine's Day, Jules wishes that Grayson would share his feelings with her; Andy "dates" Bobby; and Travis ask Laurie's help to buy a nice gift for Kirsten.

When Jules starts meddling in Travis' life, Ellie tells her to back off; Bobby and Laurie want to expose the world to their Penny Can game; Grayson learns about friendship from Andy.

[title] (Hi Dance Fans, Please Still Be There...) Jules tries to show Ellie having a baby was harder in her twenties; Andy becomes Laurie's wingman; Bobbie tries to wake up earlier.

Jules faces her fear of public humiliation when she decides to do some charity work; Laurie surprises everyone with her wits in a game of trivia.