António de Noronha descended from Pedro de Noronha, Archbishop of Lisbon and a grandson of King Fernando I of Portugal (through his mother Infanta Isabel) and of King Henry II of Castile (through his father Alfonso, Count of Noroña y Gigon).
In the 18th century this family received new honours: a royal decree of King John V of Portugal, issued on January 21, 1714, created the title of Marquis of Angeja (in Portuguese Marquês de Angeja) and granted it to Dom Pedro António de Noronha, 2nd Count of Vila Verde.
In 1833, these two titles were inherited by a collateral branch of the family: the Noronhas, Counts of Peniche.
Due to different heritages and marriages some other family names were added (such as, Camões, Albuquerque Moniz e Sousa, Azevedo Coutinho) but the original Noronha was always kept.
The Archbishop had royal ancestry both through his mother (Isabel of Portugal, a natural daughter of King Ferdinand I of Portugal) and through his father (Alfonso, Count of Noroña y Gigón, a natural son of King Henry II of Castile).