[1] On 17 November 1824, she married Count Filippo Camerata-Passionei di Mazzoleni (1805–1882) in Florence.

They had one son, Charles Félix Jean-Baptiste Camerata-Passionei di Mazzoleni, born in 1826.

The couple separated shortly after their son's birth, and Elisa moved to Trieste, where she contacted other exiled members of the Bonaparte family to try to re-establish Napoleon's only son, Napoleon François, on the throne of France.

There, she obtained the title of maîtres des requêtes au Conseil d'État for her son, but he could not withstand the pressure of court life and died at the age of 26, under mysterious circumstances.

Deeply affected by her son's death, Elisa left the court and, after a brief stay in the Veneto, settled for good in Brittany, where she devoted herself to tilling her lands and creating a farm and several fisheries.