Minnesota State Highway 249 was a highway in southeast Minnesota, which ran from its intersection with State Highways 44 and 76 in Caledonia and continued east to its eastern terminus at its intersection with State Highway 26 in Crooked Creek Township, south of Reno.

In the present day, nearly all of the route is known as Houston County Road 249.

The highway was legally defined as Legislative Route 249 in the Minnesota Statutes § 161.115(180).

Highway 249 was authorized on July 1, 1949[1] and removed in 1989.

The entire highway was in Houston County.