[5] Part of the County is situated on the Haldimand Tract,[6][7] traditional territory of the Neutral, Mississauga, and Haudenosaunee peoples.

[12] Erected by the provincial and federal governments, historic plaques and monuments in Brant County indicate a long and varied history which include many aspects related to the First Nations.

In 1784, the Crown granted Joseph Brant and his followers a land treaty along the Grand River to replace what they had lost in New York State at the Sandusky Council after the Revolution.

[15] In 1904 the chapel received Royal status by King Edward VII in memory of the longstanding alliance.

Her Majesty's Royal Chapel of the Mohawks is an important reminder of the original agreements made with Queen Anne in 1710.

[17] Significant to the county, gypsum was discovered in 1793 on the east bank of the Grand River in what became Paris during a survey for the British Home Department.

In addition to successful farmers in the area, the community of 1000 people (Americans, Scottish, English, and Irish) was thriving.

A great deal of plaster was being exported and there were three mills, a tannery, a woolen factory, a foundry, and numerous tradesmen.

The 1814 Battle of Malcolm's Mills during the War of 1812 took place at what is now Oakland when American forces attacked the local regiments.

[15] Chief Brant was elected to Legislative Assembly of Upper Canada for Haldimand in 1830 and was the first aboriginal Canadian in Parliament.

His daughter, the Mohawk poet E. Pauline Johnson (Tekahionwake), gained great acclaim across Canada.

[15][22] Brant County saw relatively early railway development in Ontario's history, as it lay nearby and between major mid-19th century centres such as Toronto and London.

[23] The branch line, as built, connected to the roughly east–west mainline at a junction in Brant County located at a key point aligned between four major manufacturing and administrative centres in the area: Brantford, Galt, Hamilton, and London.

[23] This early construction date has led to some Ontario rail history writers such as Joachim Brouwer and Ron Brown to argue that Harrisburg was the first railway junction in Canada, and that the branch line to Galt was the first branch line in Canadian railway history.

[28][29][30][31] Canada's first telephone factory, created and operated by James Cowherd, was also located in Brantford from about 1879 until his death in 1881.

Smaller communities in the municipality include Bishopsgate, Burtch, Cainsville, Cathcart, East Oakland, Etonia, Fairfield, Falkland, Glen Morris, Gobles, Harley, Harrisburg, Hatchley, Langford, Lockie, Maple Grove, Middleport, Mount Pleasant, Mount Vernon, New Durham, Newport, Northfield, Northfield Centre, Oakland, Onondaga, Osborne Corners, and Scotland.

The customer service offices are located in Burford, Paris, Oakland, Onondaga and St. George Ontario.

[52] The book lists the names of the Brant County men and women who served in World War II.