Courthouse Square Historic District is a national historic district located at West Plains, Howell County, Missouri.

The district encompasses 46 contributing buildings in the central business district of West Plains.

It developed between about 1881 and 1950 and includes representative examples of Italianate, Queen Anne, Romanesque Revival, Late Gothic Revival, and Art Deco style architecture.

[2] It was listed on the National Register of Historic Places in 2003.

This article about a property in Howell County, Missouri on the National Register of Historic Places is a stub.