The building and its site was listed on the National Register of Historic Places on January 6, 1993.

The hospital's east pavilion, designed by Weihe, Frick & Kruse and built in 1954.

The Cowell Memorial Hospital has a Residence Program from 1962 to 1974, noted for its work with disabled students.

National Register of Historic Places was given both for the buildings and the contribution it health care work.

[2][3][4] Some of the work noted is the called the Cowell experiment, by Ed Roberts, The Father of Independent Living.