As part of a large extension programme by the university in the early 2000s the original building and surrounding campus underwent significant restoration and modernisation; as a result, many of the original interior features of the building are no longer visible.
The estate in which the Hydropathic's building lies was sold in 1773 to Alexander Monro, who was second of three generations to be Professor of Anatomy at the University of Edinburgh.
Probably the most famous patients of Craiglockhart were the poets Siegfried Sassoon and Wilfred Owen, whose poems appeared in the hospital's own magazine called The Hydra.
[4] There is now an area within the building that celebrates the life and work of both Sassoon and Owen and their meeting at Craiglockhart.
The building then became a convent for the Society of the Sacred Heart, before serving as a Catholic teacher training college.