The film follows the research of psychiatrist Dr. Dorothy Otnow Lewis who studied the psychology of murders.

Richard Burr, Catherine Yeager, Park Dietz and Bill Hagmaier also appear in the film.

[4] The film was set to have its world premiere at South by Southwest in March 2020, however, the festival was cancelled due to the COVID-19 pandemic.

The site's critical consensus reads, "Crazy, Not Insane isn't as narratively disciplined as documentarian Alex Gibney's best work, but Dorothy Otnow Lewis' clinical analysis of murderous psychology may prompt unexpected sympathy for the devil.

"[11] On Metacritic, the film holds a rating of 78 out of 100, based on 7 critics, indicating "generally favorable reviews".