Crenshaw is a town in Panola and Quitman counties in the U.S. state of Mississippi, with a population of 885 in the 2010 census.

By the early 1900s, it had a post office, several stores, churches, schools and a combined oil mill/cotton gin.

[4] According to the United States Census Bureau, the town has a total area of 0.4 square mile (1.1 km2), all land.

As of the 2020 United States Census, there were 638 people, 351 households, and 239 families residing in the town.

26.5% of all households were made up of individuals, and 11.2% had someone living alone who was 65 years of age or older.

The nearest station is located in Marks, 19 miles (31 km) to the south.