Crestline is a census-designated place (CDP) in Cherokee County, Kansas, United States.

[2] Crestline is located on U.S. Route 400 7.5 miles (12.1 km) east of Columbus.

[4] The 2020 United States census counted 116 people, 42 households, and 20 families in Crestline.

40.5% of households consisted of individuals and 33.3% had someone living alone who was 65 years of age or older.

This article about a location in Cherokee County, Kansas is a stub.