[2] He made his professional debut with Altas on 21 October 2015 against Club Tijuana in a Copa MX quarter-finals match, ultimately winning 5–4 in a penalty shoot-out after a 2–2 tie.
[5] According to a poll held by Mexican sports newspaper Récord, its readers voted Calderón as the best player of the tournament.
[10] A week later in the second leg, he would score a bicycle kick in a 1–0 victory,[11] helping send Guadalajara to a penalty shoot-out that was eventually lost.
[13] In November 2020, facing rivals Club América during the Guardianes championship quarter-finals, he scored three times, all long-range shots from outside of the box, in the span of two legs giving Guadalajara a 3–1 aggregate victory.
[18] In September 2019, Calderón received his first call-up to the senior national team by Gerardo Martino and on 2 October 2019 in a friendly against Trinidad & Tobago, he made his debut.