Critters 4 is a 1992 American science fiction comedy horror film starring Don Keith Opper, Terrence Mann, Angela Bassett and Brad Dourif.

Unlike the first three films, this installment adopts a darker, less-comedic tone, and takes place not on Earth, but on a space station in the year 2045.

After reporting their find, the ship gets a communication from Councilor Tetra of TerraCor, who offers Buttram three times the going rate if he brings the pod to a nearby station.

The crew accepts, and decide to go to the station, only to find the facility abandoned, with the only sign of life being a malfunctioning central computer named "Angela" that only obeys orders when given the exact opposite instruction.

Ethan then uses a computer keycard he found earlier to access a report made by Dr. McCormick, who reveals that she was conducting research on various alien organisms for use as a bioweapon.

After the others find his remains, Angela announces that the reactor is leaking radiation and will go critical within hours, and starts sealing off sections of the station.

Ethan runs to warn the others just as a Terracor ship arrives, carrying Tetra, Ug and other troopers, whom hold the surviving crew at gunpoint.

Charlie and Fran rush aboard Tetra's ship to escape, but Ethan gets distracted when a Krite attacks him, forcing him to freeze it with a fuel hose.