The Crnojević printing house (Serbian: Штампарија Црнојевића, romanized: Štamparija Crnojevića) or Cetinje printing house (Serbian: Цетињска штампарија, romanized: Cetinjska štamparija), was the first printing house in Southeastern Europe; the facility operated between 1493 and 1496 in Cetinje, Zeta (modern Montenegro).

[1] It was founded by Đurađ Crnojević, the ruler of Zeta between 1490 and 1496.

[2] The printing press was operated by Serbian Orthodox monks at the supervision of Hieromonk Makarije.

Five Orthodox liturgical books were printed in this printshop: Oktoih Prvoglasnik, Oktoih Petoglasnik, Psaltir, Trebnik (Molitvenik) and Cvetni Triod.

In his 1514 letter to Ragusan senate, Ragusan nobleman Luka Primojević emphasized that he had intention to print books using the same letters used by Serbian priests in their churches, the same letters used in the Crnojević printing house which books were well respected and praised.