Crooked Little Vein is the first novel by comic book writer Warren Ellis, published by William Morrow on July 24, 2007.

The book was based on research material posted on Ellis' websites, mostly odd news items and disturbing pictures from the web that the author had found or had been sent.

[8] Michael McGill, a burned-out private eye is hired by a corrupt, heroin-addicted White House Chief of Staff to find a second "secret" United States Constitution, which had been lost in a whorehouse by Richard Nixon.

About.com reviewer Jonathan Lasser called Crooked Little Vein "an ace put-up job" and wrote that it was "evidence that freedom is more valuable than repression".

[9] Whitney Pastorek, reviewing for Entertainment Weekly, noted that the work "is not for the faint of heart" and that Ellis has "got a bright future outside of the picture books".