Her maiden voyage took place on 14 June 2006, departing Red Hook, Brooklyn (New York) for Grand Turk (Turks and Caicos Islands), Ocho Rios (Jamaica), Grand Cayman (Cayman Islands), and Port Canaveral (Florida).

[4] The United States Coast Guard was contacted shortly after and crews arrived within minutes to assist the troubled vessel.

[4] The severe listing tumbled passengers, crew members, pool water, and everything else not secured about the decks.

[5] Fourteen passengers and crew members were seriously injured, one suffering breathing difficulties after being hit in the chest by an airborne chair, and another 284 had minor injuries.

Most injuries were on the outdoor areas of Decks 15 and 16, where large beach chairs and tables hit and injured passengers.

After an internal review by Princess Cruises, its president Alan Buckelew publicly stated that "the incident was due to human error and the appropriate personnel changes have been made."

In April 2013 she sailed to Southampton and operated cruises to Northern Europe, the Mediterranean, and the Canary Islands.

Subsequently, Crown Princess returned to the United States to Fort Lauderdale, sailing Caribbean cruises until February 2014.