The Old Main building in Upland was listed on the National Register of Historic Places in 1973.

[1] The Seminary began as the Normal School of Upland, established and built by the president of the board of directors of the American Baptist Publication Society, John Price Crozer.

[8] Crozer allowed the Union army to use the building as a hospital during the Civil War.

[9] After the war, the building was repossessed by Crozer and subsequently sold to Colonel Theodore Hyatt for use as the Pennsylvania Military Academy until 1868.

When Old Main was vacated by the Pennsylvania Military Academy his family converted the school to the Crozer Theological Seminary in his honor.