The Cruzzini (French pronunciation: [kʁutsini]; or Cruzini; Corsican: Cruzinu) is a river in the center of the department of Corse-du-Sud, Corsica, France.

[1] It rises in the commune of Pastricciola on the border with the department of Haute-Corse to the south of the 2,021 metres (6,631 ft) Punta all'Altore.

In its upper section it flows past the villages of Chiusa, Pastricciola, Rezza and Azzana, and is followed by the D104 or D4 road on its right (north) bank.

[2] There is a legend that three brothers, Liamone, Golo and Tavignano, suffered from the cold in the mountains of the central chain of Corsica.

[7] The valley is covered by a dense Maquis shrubland except in the immediate vicinity of the villages, which are surrounded by terraced gardens and a few olive or chestnut groves.

[9] In its upper reaches the crest that separates the valley of the Cruzini from that of the Fiume Grossu to the north has been designated a Zone naturelle d'intérêt écologique, faunistique et floristique (ZNIEFF).