Ctenus

157, see text Ctenus is a genus of wandering spiders first described by Charles Athanase Walckenaer in 1805.

[2] It is widely distributed, from South America through Africa to East Asia.

[1] Little is known about the toxic potential of the genus Ctenus; however, Ctenus medius has been shown to share some toxic properties with Phoneutria nigriventer, such as proteolytic, hyaluronidase and phospholipase activities, in addition to producing hyperalgesia and edema.

[3] The venom of C. medius interferes with the complement component 3 (C3) of the complement system; it affects the central factor of the cascades of the complement, and interferes with the lytic activity of this system, which causes stronger activation and consumption of the complement components.

Unlike C. medius, the venom of P. nigriventer does not interfere with lytic activity.