This instrument has had its prominent performers like the legendary Ladislao Martínez Otero, known as "El Maestro Ladi", the great Nieves Quintero, the renowned Maso Rivera, Iluminado Dávila Medina, Yomo Toro and Edwin Colón Zayas.

The project met with only limited success and today most of these variants are rare, with the cuatro tradicional surviving as the standard instrument.

The Cuatro Project is also dedicated to promoting and preserving the Puerto Rican décima verse form and the traditional song as created by its greatest troubadours, living and past.

Cumpiano and cultural researcher David Morales produced another DVD documentary THE DÉCIMA BORINQUEÑA: An ancient poetic singing tradition, directed by Myriam Fuentes.

[9] Jon Anderson used a cuatro on the Yes album Tormato,[10] although the sleeve-notes misdescribe the instrument as an Álvarez ten string guitar.

Puerto Rican singer-songwriter Christian Nieves played a cuatro on the 2017 hit single "Despacito" by Luis Fonsi featuring Daddy Yankee;[11] the instrument, as strung for left-handed playing, appears at 3:32 of the song's official music video, which became the most-viewed video on YouTube on August 4, 2017.