Cueva Antón is a paleoanthropological and archeological site in the Region of Murcia of southeast Spain.

The cave is located about 60 kilometers from the Mediterranean port city of Cartagena inland in the territory of the municipality of Mula.

It was eroded by the Río Mula and served as a cave in the Middle Palaeolithic inhabited by Neanderthals.

The cave became internationally known in 2010, after a shell at least 43,000 years old with adhering orange pigment was discovered there.

The colonization of the Iberian Peninsula by modern man ( Homo sapiens ) took place only several thousand years after the creation of the jewelry from the Cueva Antón.