Whether by fate or other circumstances, Trevor Pierce (Bobby Cannavale) is under the care of psychiatrist and self-help author Dr. Claire McCrae (Sarah Paulson) whose own work is often based in romantic relationships.

Claire's philosophy on true love is that it's the result of building friendship and compatibility.

Daily Variety had reported as early as October 2007 that ABC had approved a new version of the series,[3] to be set in Los Angeles, as part of a one-year development deal between ABC Studios and series creator Rob Thomas.

A follow-up report published in The Hollywood Reporter in March 2008[4] noted that the network had received initial scripts for the series and approved production for episodes to be broadcast as a mid-season replacement for 2008 or 2009.

As production developed, the series' primary setting was shifted to New York City.