The permanent collection includes works by Picasso, Matisse, Monet, O'Keeffe, Calder, Scheier and Goldsmith, John Singer Sargent, Frank Lloyd Wright, and Andrew Wyeth.

After his third wife's death in 1915, a board of trustees was appointed to carry out the Curriers' wishes that a structure be constructed.

In 1982, new pavilions, designed by the New York firm Hardy Holzman Pfeiffer, were built to accommodate the museum's growing collections, programs and staff.

In 1990 it was opened to the public so that visitors could enjoy a private world from the 1950s and 1960s including the Zimmermans' unique collection of modern art, pottery, and sculpture.

In 2019, the Currier Museum of Art acquired Kalil House, a second private residence in Manchester designed by Wright, for $970,000.

[6] It is made of concrete blocks, 12 x 24 inches, laid without mortar, with rebar placed both horizontally and vertically in semicircular joints.

[7] Upon his death in 2001, trustee Henry Melville Fuller left the Currier Museum $43 million, half designated for the art purchase fund.