Curtis Creek is a tidal creek located in Baltimore City and Anne Arundel County, Maryland.

It is a tributary of the cove Curtis Bay and is adjacent to the west of the South Baltimore community of Curtis Bay.

It flows north about 2.5 miles (4.0 km) into Curtis Bay (which now lies in the City of Baltimore) which opens to the east into the main branch and stem of the Patapsco River (serving as the Port of Baltimore) and Chesapeake Bay.

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